|
Education
- Yale University 2004 - 2006 Ph.D. in Computational Chemisty.
- Adviser: Dr. William L. Jorgensen
- Yale University 2002 - 2004 M.S. in Chemistry
- Adviser: Dr. William L. Jorgensen
- St. John's University 2000 - 2002 M.S. in Synthetic Organic Chemistry, GPA 3.9
- Adviser: Dr. Victor O. Cesare
- Hobart and William Smith Colleges 1996 - 2000 B.S. cum laude major: chemistry
- Dean’s List 1997-2000, Girl Scout Brittenstool Scholarship 1996-2000, Inducted into Phi Lamda Upsilon and Sigma Xi 2000, Chemistry Achievement Award of the Rochester Section of the American Chemical Society 2000, Helen Heath Scholar 1996-1997, American Chemical Society certified major in chemistry.
Experience
-
Director, Business Strategy & Procurement
Catholic Medical Mission Board 2010 - 2011
- Strategic planning and development (USA/Latin America/Africa/Asia)
- Negotiate and manage contractual agreements and interactions
- Oversee the delivery of $300M of pharmaceuticals and medical supplies to Latin America, Africa, Asia
- Improved internal supply chain via technology implementations
- Partnerships in El Salvador, Haiti, Nicaragua, Peru
- Implemented salesforce
-
Regional
Alliance and Development Manager
Multiple Myeloma Research Foundation 2008 - 2010
- Responsible for the expansion of efficient and effective
development programs to enhance cultivation and reinvestment of the
MMRF's annual revenue budget of $22MM.
- Establish relationships with top national hematology oncologists (heme-onc)
KOLs as well as local oncologists.
- Cultivate high net worth individuals to foster relationships
resulting in financial donations. Oversee the generation of $3.8MM in
revenue from major donors.
- Planned and executed the MMRF’s Investors Summit, which involved
identification of national myeloma Key Opinion Leaders (KOLs), speaker
training of MMRF messaging, and management of event consultants while
working closely with our marketing strategy and scientific
communications team. Advocated to stream the Summit live over the
internet to high net worth individuals and their medical advisors not
in attendance. Raised $350k in revenue from Investors Summit.
- Oversee $2.5MM in revenue generation from programs such as Online
Giving, Planned Giving, Federal Campaigns, Annual Appeals, and
Newsletters.
- Created, managed, and executed online marketing strategy which
resulted in a 29% increase in total 2008 online giving in comparison
to 2007.
- Gave sales/donor presentations to high-net worth individuals as a
team and alone.
- Participated in key external and internal scientific meetings.
-
Medical Strategist
81qd 2007 - 2008
- Team leader on business development and life cycle management for a
strategic consulting company in the design of custom enterprise
technology solutions.
- Expert status in the process of identification of Key Opinion
Leaders (KOLs) for breast cancer, colorectal cancer, growth hormones,
renal cell carcinoma, chronic lymphocytic leukemia, glioblastoma
multiforme, and lupus.
- Managed a team to perform targeted influence mapping of KOLs via
natural language processing.
- Supervised all quality assurance pertaining to projects with art
directors, copy editors, account executives, research analysts, and
programmers to ensure the medical accuracy and medical strategy
direction of client’s brand.
-
Post-Doctoral Fellow
sanofi-aventis 2006 - 2007
- Lead a cross-departmental team and an outside contractor to create
a prototype corporate metabolism database.
- Managed all aspects of the metabolism database starting with the
design all the way through to the presentation of the corporate
database to Global Department heads.
- Successfully delivered the project on time and under budget.
- Formulated and tested strategies to predict cytochrome P450
metabolic sites of potential drugs by evaluating the strengths and
limitations of MetaSite. Propensity of metabolism for certain
functional groups were also tabulated and ranked.
- Explored the use of different docking programs to generate
reasonable conformations to be used for MetaSite in hopes of
increasing accuracy of predictions.Devised a scientific strategy to efficiently share metabolism data quickly between departments.
Publications
Lengyel, I.; Taldone, T.; Lyons, T.M.; Cesare, V.O. "Full Characterization, Thermal Decomposition, and Reactions of 1-(2-adamantyl)-3-(1-adamantyl)aziridin-2-one." Accepted by the Journal of Heterocyclic Chemistry
Barreiro, G.; Guimaraes, C. R. W.; Tubert-Brohman, I.; Lyons, T. M.; Tirado-Rives, J.; Jorgensen, W. L. "Search for Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase Using Chemical Similarity, Molecular Docking, and MM-GB/SA Scoring." J. Chem. Inf. Model. 47, 2416-2428 (2007)
Cesare, V.O.; Lyons, T.M.; Lengyel, I. "A High-Yielding Synthesis of a-Lactams (Aziridinones)." Synthesis, 12, 1716-1720 (2002).
Selected Presentations
T.M. Lyons, I. Tubert-Brohman, and W.L. Jorgensen “A Priori pKa predictions: Investigation of steric effects on the basicity of substituted pyridines via MC/FEP calculations” National ACS Meeting, New York, NY September 2003.
T.M. Lyons, I. Tubert-Brohman, and W.L. Jorgensen “A Priori pKa calculations and the Steric Effect on a Series of Substituted Pyridine Molecule” Yale University Biophysical Symposium, New Haven, CT May 2003
T.M. Lyons, V.O. Cesare, and I. Lengyel "A New Synthesis of a-Lactams (aziridinones).” National ACS Meeting Orlando, FL April 2002
T.M. Lyons and Carol Parish "Docking Studies Using the Low Mode Conformational Search Algorithm” National ACS Meeting San Francisco, CA March 2000
T.M. Lyons "Conformational Analysis of FDA Approved HIV Protease Inhibitors” Hobart and William Smith Colleges chapter Phi Beta Kappa Student Showcase Invited Talk Geneva, NY May 1999
T.M. Lyons and Carol Parish "Conformational Comparison of FDA Approved HIV Protease Inhibitors” National ACS Meeting Boston, MA August 1998.
Grants
NIH Biophysical Training Grant Recipient 2004 - 2005
Frederick W. Heyl Fellowship and Teaching Fellowship 2003 – 2004
Yale University and Teaching Fellowship 2002 - 2003
St. John's University Graduate Assistantship 2000 - 2002
Council on Undergraduate Research Summer Research Fellowship Summer 1999
Hobart and William Smith Colleges Provost Summer Fellowship Summer 1998
Teaching Experience
Spring 2004 Advanced Organic Chemistry - Yale University
Fall 2003 Organic Chemistry - Yale University
Spring 2003 and Fall 2002 General Chemistry Laboratory - Yale University
Spring 2002 Organic Chemistry Laboratory - St. John's University
Fall 2002 Organic Chemistry Laboratory - St. John's University
Spring 2001 Organic Chemistry Laboratory and General Chemistry Laboratory - St. John's University
Fall 2000 Organic Chemistry Laboratory and General Chemistry Laboratory - St. John's University
|